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Updated: Jul 26, 2026

11:06
Identifying DNA Mutations in Purified Hematopoietic Stem/Progenitor Cells
Published on: February 24, 2014
Microsatellites in the eukaryotic DNA mismatch repair genes as modulators of evolutionary mutation rate
D K Chang1, D Metzgar, C Wills
1Department of Medicine and Cancer Center, University of California San Diego, La Jolla, California 92093-0688, USA.
Genome Research
|July 4, 2001
Abstract
No abstract available in PubMed .
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Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
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