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Deletion mapping of the encephalomyocarditis virus primary cleavage site
1Institute for Molecular Virology, University of Wisconsin, Madison, Wisconsin 53706, USA.
Journal of Virology
|July 4, 2001
Abstract:
The cotranslational, primary self-cleavage reaction of cardiovirus polyprotein relies on a highly conserved, short segment of amino acids at the 2A-2B protein boundary. The amino terminus of the required element for encephalomyocarditis virus has now been mapped to include Tyr(126) of the 2A protein, the 18th amino acid before the cleavage site.