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Fluoride release from glass ionomer activated with fluoride solutions
C L Dhondt1, E A De Maeyer, R M Verbeeck
1Department of Dental Materials Science, Institute for Biomedical Technologies, Ghent University, Belgium.
Journal of Dental Research
|July 5, 2001
Summary
Fluoride release from glass-ionomer cements (GICs) involves both easily accessible and strongly bound fluoride. Higher fluoride concentrations in activating solutions increase release, while maturation reduces it.
Area of Science:
- Dental Materials Science
- Biomaterials Chemistry
Background:
- The fluoride release mechanism from glass-ionomer cements (GICs) remains complex and not fully elucidated.
- Understanding ion release is crucial for optimizing GIC performance and therapeutic effects.
Purpose of the Study:
- To investigate fluoride and alkali metal ion release from a simplified GIC formulation.
- To analyze the impact of fluoride concentration and maturation on ion release kinetics.
Main Methods:
- A simple GIC formulation using fluoride- and alkali metal-free glass was prepared.
- The GIC was activated with sodium fluoride (NaF) or potassium fluoride (KF) solutions.
- Elution studies were conducted in water at 37°C for 168 days.
Main Results:
- Cumulative fluoride release exhibited an initial burst followed by a slow, prolonged release.
- Fluoride release increased with higher concentrations in activating solutions, irrespective of the alkali metal used.
- Pre-elution maturation reduced both fluoride and alkali metal ion release, with ions showing incomplete correlation.
Conclusions:
- Fluoride release from GICs is a multifaceted process involving both loosely and strongly bound fluoride.
- The setting reaction influences fluoride binding, contributing to long-term ion release.
- Maturation plays a significant role in modulating ion diffusion from GICs.
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