Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Automated serological compatibility testing using a solid-phase test and standard laboratory equipment.

N Ostendorf1, D Niefhoff, U Cassens

  • 1Department of Transfusion Medicine and Transplantation Immunology, Westfaelische Wilhelms-Universitaet, Münster, Germany. transfusionsmedizin@uni-muenster.de

Vox Sanguinis
|July 5, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reversibility of platelet P2Y12 inhibition by platelet supplementation: ex vivo and in vitro comparisons of prasugrel, clopidogrel and ticagrelor.

Journal of thrombosis and haemostasis : JTH·2018
Same author

Detection of bacterial contamination in platelet concentrates by a sensitive flow cytometric assay (BactiFlow): a multicentre validation study.

Transfusion medicine (Oxford, England)·2012
Same author

Inter-laboratory comparison of different rapid methods for the detection of bacterial contamination in platelet concentrates.

Vox sanguinis·2011
Same author

The isotype of autoantibodies influences the phagocytosis of antibody-coated platelets in autoimmune thrombocytopenic purpura.

Scandinavian journal of immunology·2011
Same author

[Risks and side effects of blood transfusion].

Der Orthopade·2009
Same author

An HLA-DR11/DQ3 haplotype with a DRB1*0301 sequence motif in the third hypervariable region of the HLA-DR beta-1 chain: molecular and serological analysis of its generation in a European Caucasian family.

Tissue antigens·2009
Same journal

Barriers and enablers to non-remunerated plasma donation: A meta-synthesis of the qualitative literature using the theoretical domains framework.

Vox sanguinis·2026
Same journal

Haemolytic disease of the foetus and newborn due to anti-M: A systematic review.

Vox sanguinis·2026
Same journal

In vitro evaluation of apheresis platelet and plasma products collected and stored in non-DEHP disposable sets.

Vox sanguinis·2026
Same journal

Survey of national and regional rare donor programmes regarding Immunoglobulin A deficiency.

Vox sanguinis·2026
Same journal

Fibrinogen recovery in cryoprecipitate prepared from thawed plasma stored for 5 days post-thaw.

Vox sanguinis·2026
Same journal

Abstracts of the 39th International Congress of the ISBT, Kuala Lumpur, Malaysia, 20-24 June 2026.

Vox sanguinis·2026
See all related articles

A new semi-automated cross-match procedure using solid-phase microplate technology is feasible for routine blood bank testing. This method offers comparable sensitivity and stability for red blood cell samples.

Area of Science:

  • Transfusion Medicine
  • Clinical Laboratory Science
  • Immunology

Background:

  • Blood cross-matching is critical for preventing transfusion reactions.
  • Traditional methods can be labor-intensive and time-consuming.
  • Advancements in laboratory automation are needed to improve efficiency.

Purpose of the Study:

  • To evaluate the feasibility of a semi-automated cross-match procedure.
  • To assess the performance of a solid-phase microplate test in a routine laboratory setting.

Main Methods:

  • A semi-automated cross-match procedure utilizing a commercial solid-phase microplate test was developed.
  • The new method was compared against conventional spin tube and gel centrifugation techniques.
  • Sample stability from red cell concentrates was assessed over their shelf-life.

Related Experiment Videos

Main Results:

  • The semi-automated method demonstrated sensitivity and non-specific reaction rates comparable to existing techniques.
  • Red blood cell samples remained stable throughout the product's shelf-life.
  • The procedure was successfully implemented in a routine laboratory environment.

Conclusions:

  • The semi-automated cross-match procedure is a viable and efficient alternative for high-volume blood banking.
  • This method streamlines processing while maintaining accuracy and reliability.
  • Successful integration into routine laboratory workflows was achieved.