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Post-traumatic endophthalmitis involving Clostridium tetani and Bacillus spp

M N Iyer1, G Kranias, M E Daun

  • 1Department of Internal Medicine, The Christ Hospital, Cincinnati, Ohio 45219, USA.

American Journal of Ophthalmology
|July 5, 2001
PubMed
Abstract

Insights

This case report details a rare instance of post-traumatic endophthalmitis caused by Clostridium tetani and Bacillus species following a penetrating eye injury. Early assessment of tetanus immunization status is crucial for patients with eye trauma.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Post-traumatic endophthalmitis is a severe ocular infection that can lead to vision loss.
  • Penetrating eye injuries pose a significant risk for developing endophthalmitis.

Observation:

  • A 25-year-old male presented with endophthalmitis after a corneoscleral laceration from a concrete reinforcement bar.
  • Vitreous cultures were positive for Bacillus species and Clostridium tetani.
  • Despite receiving a tetanus toxoid booster, the patient developed severe orbital inflammation and underwent evisceration.

Findings:

  • This is the first reported case of endophthalmitis caused by Clostridium tetani.
  • The presence of Bacillus species alongside C. tetani in the vitreous highlights polymicrobial infection risks.

Implications:

  • Patients with penetrating eye injuries require prompt assessment of tetanus immunization status.
  • Consider early intervention with tetanus toxoid booster and/or tetanus immune globulin for positive cultures.
  • This case underscores the importance of considering unusual pathogens in post-traumatic endophthalmitis.

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