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Steroid-induced hypertrophic cardiomyopathy following stem cell transplantation in a neonate: a case report

J J Lesnik1, G K Singh, I C Balfour

  • 1Department of Pediatrics, Saint Louis University School of Medicine, Cardinal Glennon Children's Hospital, St Louis, MO, USA.

Bone Marrow Transplantation
|July 5, 2001
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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...