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Related Experiment Videos

Hormones, weight change and menopause.

K M Davies1, R P Heaney, R R Recker

  • 1Creighton University, Osteoporosis Research Center, 601 North 30th Street, Omaha, NE 68131, USA.

International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity
|July 6, 2001
PubMed
Summary
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Mid-life women experience gradual weight gain regardless of menopause or hormone replacement therapy. This study found no significant impact of estrogen use or menopausal transition on long-term body weight changes.

Area of Science:

  • Endocrinology and Metabolism
  • Women's Health
  • Gerontology

Background:

  • Mid-life women often experience body weight changes.
  • Menopause and hormone replacement therapy (HRT) are potential influencing factors.

Purpose of the Study:

  • To investigate total body weight changes in mid-life women.
  • To determine the influence of menopause and estrogen use on weight trajectory.

Main Methods:

  • Retrospective analysis of body weight measurements from two cohorts of healthy women.
  • Data collected over extended periods before and after menopause, with some participants receiving HRT.

Main Results:

  • Weight increased linearly with age in both cohorts, irrespective of menopausal status.

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  • Neither menopausal transition nor estrogen replacement therapy significantly altered the rate of weight gain.

    • Conclusions:

    • Long-term body weight trajectory in mid-life women is not significantly affected by menopause or HRT.
    • Estrogen therapy does not appear to influence weight gain patterns during this life stage.