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Published on: March 27, 2018
Stroke after coronary artery bypass: incidence, predictors, and clinical outcome
S C Stamou1, P C Hill, G Dangas
1Section of Cardiac Surgery, Department of Surgery, Washington Hospital Center, Washington, DC, USA. sxs3@mhg.edu
Insights
Stroke after coronary artery bypass grafting (CABG) is a serious risk. Preoperative and postoperative factors can predict increased stroke risk, impacting patient morbidity and mortality.
Area of Science:
- Cardiovascular Surgery
- Neurology
- Critical Care Medicine
Background:
- Postoperative stroke is a significant adverse event following coronary artery bypass grafting (CABG).
- Understanding the factors contributing to stroke after CABG is crucial for patient outcomes.
Purpose of the Study:
- To identify risk factors, prevalence, and prognostic implications of stroke in patients undergoing CABG.
- To analyze preoperative and postoperative variables associated with stroke after cardiac surgery.
Main Methods:
- A retrospective analysis of 16,528 consecutive patients who underwent CABG.
- Logistic regression analysis was employed to identify predictors of postoperative stroke.
Main Results:
- The prevalence of postoperative stroke was 2% (333 patients).
- Significant risk factors included chronic renal insufficiency, recent myocardial infarction, prior cerebrovascular accident, carotid artery disease, hypertension, diabetes, advanced age (>75 years), left ventricular dysfunction, low cardiac output syndrome, and atrial fibrillation.
- Postoperative stroke was associated with prolonged hospital stay and increased in-hospital mortality (14% vs. 2.7%).
Conclusions:
- Stroke following CABG is linked to substantial short-term morbidity and mortality.
- Preoperative and postoperative clinical factors effectively predict the risk of stroke after CABG.
Background And Purpose:
Early postoperative stroke is a serious adverse event after coronary artery bypass grafting (CABG). This study sought to investigate risk factors, prevalence, and prognostic implications of postoperative stroke in patients undergoing CABG.
Methods:
We investigated the predictors of postoperative stroke (n=333, 2%) in 16 528 consecutive patients who underwent CABG between September 1989 and June 1999 in our institution. Predictors of postoperative stroke were identified by logistic regression analysis.
Results:
Among the preoperative and postoperative factors, significant correlates of stroke included (1) chronic renal insufficiency (P<0.001), (2) recent myocardial infarction (P=0.01), (3) previous cerebrovascular accident (P<0.001), (4) carotid artery disease (P<0.001), (5) hypertension (P<0.001), (6) diabetes (P=0.001), (7) age >75 years (P=0.008), (8) moderate/severe left ventricular dysfunction (P=0.01), (9) low cardiac output syndrome (P<0.001), and (10) atrial fibrillation (P<0.001). Postoperative stroke was associated with longer postoperative stay (11+/-4 versus 7+/-3 days for patients without stroke, P<0.001) and with higher in-hospital mortality (14% versus 2.7% for patients without stroke; P<0.001).
Conclusions:
Stroke after CABG is associated with high short-term morbidity and mortality. Increased stroke risk can be predicted by preoperative and postoperative clinical factors.
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