Related Experiment Video
Updated: Oct 5, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
[Carcinoma of the esophagus--actual epidemiology in Germany]
E Bollschweiler1, A H Hölscher
1Klinik und Poliklinik für Visceral- und Gefässchirurgie der Universität zu Köln. Elfriede.Bollschweiler@medizin.uni-koeln.de
Abstract:
Over the last years the incidence of esophageal cancer in Germany has been rising. One of the reasons of this rise is the increase of adenocarcinoma (AC) of the esophagus, a nearly unknown diagnosis 30 years ago. The incidence of squamous cell carcinoma (SCC) is rising, too. The main risk factors for the development of SCC as well as for AC are heavy smoking and alcohol. Barrett's esophagus is predominantly developing in men after a longer lasting gastroesophageal reflux. In consequence, AC of the esophagus will be observed mostly in men. Patients with AC differ from patients with SCC by a smaller number of concomitant diseases, which are often caused by obesity of patients with AC. The preoperative risk factors of patients with SCC are caused by tobacco and alcohol. Only patients with early cancer (pT1) of the esophagus have a good prognosis with a 5-year survival rate of 83% for AC and 63% for SCC.
Related Concept Videos
Barrett Esophagus-I: Introduction
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more similar...
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Gastroesophageal Reflux Disease
Esophagus
The movement of edibles from the pharynx into the esophagus is facilitated by the upper esophageal sphincter, which is formed primarily by the...
Esophageal Achalasia

