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Updated: Oct 5, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
Published on: January 16, 2019
Cocaine-induced torsades de pointes in idiopathic long Q-T syndrome
N Singh1, H K Singh, P P Singh
1Division of Cardiology, Long Island College Hospital, Brooklyn, NY, USA.
Abstract:
Torsades de pointes is a ventricular tachycardia characterized by the QRS complexes of changing amplitude that appear to twist around an isoelectric line. It usually precipitates in the setting of underlying Q-T interval prolongation, which has both congenital and acquired causes. The common acquired causes of torsades precipitation are medications, electrolyte imbalance, and severe bradycardia. This report presents a case of torsades de pointes that was precipitated by substance abuse in a patient with idiopathic long Q-T syndrome and required several treatment modalities.
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