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Updated: Aug 5, 2026

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
Published on: February 19, 2019
Grade and stage in chronic hepatitis
1Department of Pathology, Children's and Women's Health Centre of British Columbia, 4450 Oak Street, Vancouver, British Columbia, Canada V6H 3V4.
Abstract:
The liver biopsy is essential to the investigation and management of chronic liver disease. The pathologist provides an etiologic diagnosis, reports the grade of disease activity and stage of fibrosis, and comments on any response to therapy. Recent progress in our understanding of chronic hepatitis, its causes, prognosis, and therapy, has influenced the revision of its nomenclature and classification. The use of a descriptive or numerical scoring system allows the pathologist to provide reproducible, clinically relevant information in the surgical pathology report.
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