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Updated: Jul 9, 2026

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
Circumstances at HIV diagnosis and progression of disease in older HIV-infected Americans
D S Zingmond1, N S Wenger, S Crystal
1Division of General Internal Medicine and Health Services Research, UCLA Department of Medicine, 911 Broxton Plaza, Los Angeles, CA 90095-1736, USA. dzingmond@mednet.ucla.edu
Objectives:
This study identified age-related differences in diagnosis and progression of HIV by analyzing a nationally representative sample of HIV-infected adults under care in the United States.
Methods:
We compared older (> or = 50 years) and younger participants stratified by race/ethnicity. Regression models controlled for demographic, therapeutic, and clinical factors.
Results:
Older non-Whites more often had HIV diagnosed when they were ill. Older and younger patients were clinically similar. At baseline, however, older non-Whites had fewer symptoms and were less likely to have AIDS, whereas at follow-up they had a trend toward lower survival.
Conclusions:
Later HIV diagnosis in non-Whites merits public health attention; clinical progression in this group requires further study.
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