Evaluation of immunoglobulin G synthesizing plasma cells in periapical granuloma and cyst

N Grover1, N N Rao, M S Kotian

  • 1Departments of Oral Pathology and Community Medicine, College of Dental Surgery, Manipal and K.M.C. Mangalore, India.

Immunoglobulin synthesizing plasma cells for IgG were quantitated in 20 periapical granulomas and 20 periapical cysts, using unlabelled antibody peroxidase-antiperoxidase complex method. Result showed that immunoglobulin G producing plasma cells were predominant in periapical cyst as compared with periapical granuloma. A statistical significant relation was observed between these two lesions.

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