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Radiotherapy for genital extramammary Paget's disease in situ
G A Moreno-Arias1, C Conill, A Castells-Mas
1Department of Dermatology, Hospital Clinic, University of Barcelona, Villaroel 170, 08036 Barcelona, Spain.
Background:
Radiotherapy as a first-choice treatment for extramammary Paget's (EMP) disease in situ has been seldom used.
Objective:
To review the most relevant aspects of radiotherapy as first-choice treatment in selected cases of anogenital EMP disease in situ.
Methods:
Two men with an age range of 71-79 years (mean age 75 +/- 5.6 years) with EMP disease in situ localized in the genital region were treated by means of X-rays of 100 kV, 440 cGy/day, 3 days a week over 3 weeks until a total dose of 3960 cGy was completed.
Results:
Complete regression of EMP disease in situ was observed in both patients after radical radiation therapy and neither local recurrences nor internal malignancies have been documented.
Conclusion:
Radiotherapy is a curative treatment in selected cases of EMP disease in situ affecting large areas of the anogenital region.