Sendai virus C protein physically associates with Stat1

K Takeuchi1, T Komatsu, J Yokoo

  • 1Department of Microbiology, Fukui Medical University, Shimoaizuki 23-3, Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan.

Summary

Sendai virus C protein binds to Signal transducer and activator of transcription 1 (Stat1), forming large complexes. This interaction inhibits interferon-stimulated gene activation, revealing a key viral immune evasion mechanism.

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