Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microembolism in Cerebral Angiography.

Hugh Markus1

  • 1Department of Neurology, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, United Kingdom.

Echocardiography (Mount Kisco, N.Y.)
|September 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of carotid atherosclerosis in stroke.

Practical neurology·2024
Same author

Immune regulation and blood-brain barrier permeability in cerebral small vessel disease: study protocol of the INflammation and Small Vessel Disease (INSVD) study - a multicentre prospective cohort study.

BMJ open·2024
Same author

The contribution of competing mechanisms in stroke despite anticoagulation in patients with atrial fibrillation.

European stroke journal·2023
Same author

Tenecteplase versus alteplase for stroke thrombolysis evaluation (TASTE): A multicentre, prospective, randomized, open-label, blinded-endpoint, controlled phase III non-inferiority trial protocol.

International journal of stroke : official journal of the International Stroke Society·2023
Same author

VasCog 2021 Virtual Report and Abstracts.

Cerebral circulation - cognition and behavior·2022
Same author

Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL).

Practical neurology·2021

Transient high-intensity embolic signals detected during cerebral angiography are often asymptomatic air emboli. Techniques like reducing contrast injection speed can minimize these signals.

Area of Science:

  • Neurology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Transcranial Doppler (TCD) monitoring detects embolic signals in cerebral angiography.
  • These signals are frequent during contrast injection and catheter manipulation.
  • Current understanding suggests most signals are asymptomatic air emboli.

Purpose of the Study:

  • To investigate the nature and origin of transient high-intensity embolic signals during cerebral angiography.
  • To explore methods for reducing the occurrence of these embolic signals.
  • To assess the potential for distinguishing between air and particulate emboli.

Main Methods:

  • Utilized transcranial Doppler monitoring of middle cerebral artery blood flow velocity.
  • Analyzed signal occurrences during contrast injection, catheter/wire manipulation, and saline flushes.

Related Experiment Videos

  • Referenced experimental flow and animal models to determine signal composition.

    • Main Results:

    • Embolic signals are frequently observed during cerebral angiography, particularly with contrast injection.
    • Experimental studies indicate the majority of these signals are likely air emboli.
    • Reducing contrast injection speed and allowing contrast to stand before injection can decrease signal frequency.

    Conclusions:

    • Most embolic signals during cerebral angiography appear to be asymptomatic air emboli.
    • Techniques exist to reduce the introduction of air emboli during the procedure.
    • Future technological advancements may enable differentiation between air and particulate emboli.