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Molecular solutions to mammalian lens transparency
P Donaldson1, J Kistler, R T Mathias
1Department of Physiology, School of Medicine, University of Auckland, Auckland, New Zealand.
Abstract:
The mammalian lens generates an internal microcirculation that maintains transparency in the avascular lens. Significant progress has been made in characterizing the membrane transport proteins associated with this circulation. By combining physiological and molecular evidence, a more comprehensive understanding of normal lens function and cataractogenesis is emerging.