Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Of slow waves and spike patches.

W J Lammers1, J R Slack

  • 1Department of Physiology, Faculty of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates. wlammers@uaeu.ac.ae

News in Physiological Sciences : an International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society
|July 10, 2001
PubMed
Summary

Slow waves in the small intestine generate calcium spikes to drive mechanical movements. Electrical mapping shows distinct propagation patterns for slow waves and calcium spikes, indicating different underlying mechanisms and cell networks.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The impact of biliary drainage on chemotherapy initiation and survival in patients with non-resected perihilar cholangiocarcinoma: a population-based study in the Netherlands.

Scandinavian journal of gastroenterology·2026
Same author

How the concept of biochemical response influenced the management of primary biliary cholangitis over time.

The Netherlands journal of medicine·2016
Same author

Inhomogeneities in the propagation of the slow wave in the stomach.

Neurogastroenterology and motility·2015
Same author

Slow wave dysrhythmias in the diabetic small intestine.

Neurogastroenterology and motility·2015
Same author

Introduction to 'electrical propagation in smooth muscle organs'.

Acta physiologica (Oxford, England)·2014
Same author

Arrhythmic substrate, slowed propagation and increased dispersion in conduction direction in the right ventricular outflow tract of murine Scn5a+/- hearts.

Acta physiologica (Oxford, England)·2014

Area of Science:

  • Gastroenterology
  • Physiology
  • Cell Biology

Background:

  • Slow waves are crucial for intestinal motility, inducing mechanical movements via local calcium spikes.
  • Understanding the propagation mechanisms of these electrical events is key to comprehending gut function.

Purpose of the Study:

  • To investigate the distinct propagation characteristics of intestinal slow waves and calcium spikes.
  • To elucidate the underlying cellular mechanisms and networks responsible for their propagation.

Main Methods:

  • High-resolution electrical mapping of the small intestine.
  • Analysis of propagation patterns of slow waves and calcium spikes.

Main Results:

  • Fundamental differences in propagation were observed between slow waves and calcium spikes.

Related Experiment Videos

  • Slow waves and calcium spikes exhibit distinct spatial and temporal dynamics.

    • Conclusions:

    • Slow waves and calcium spikes are propagated by separate mechanisms.
    • Different cell networks likely mediate the propagation of slow waves and calcium spikes in the small intestine.