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Updated: Aug 1, 2026

Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen
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Possible roxithromycin-induced fulminant hepatic failure in a child

K L Easton-Carter1, W Hardikar, A L Smith

  • 1Department of Pharmacy, Royal Children's Hospital, Melbourne, Victoria, Australia.

Pharmacotherapy
|July 11, 2001
PubMed
Summary

A new pediatric antibiotic, roxithromycin, caused severe liver injury in a 5-year-old boy, necessitating a liver transplant. This highlights the potential for serious hepatic complications in children treated with this drug.

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