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Related Experiment Videos

Marihuana and the cardiovascular system.

S C Clark

    Pharmacology, Biochemistry, and Behavior
    |March 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Acute marihuana use causes tachycardia and conjunctival injection. Blood pressure effects vary with posture, but overall, marihuana poses no significant cardiovascular hazard to healthy individuals.

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    Area of Science:

    • Cardiovascular Physiology
    • Pharmacology

    Background:

    • Cardiovascular effects of marihuana (cannabis) are well-documented.
    • Acute administration consistently produces tachycardia and conjunctival injection.

    Purpose of the Study:

    • To summarize the cardiovascular actions of acute marihuana administration in humans.
    • To assess potential cardiovascular risks associated with marihuana use.

    Main Methods:

    • Review of existing physiological and pharmacological studies on marihuana's cardiovascular effects.
    • Analysis of blood pressure, heart rate, limb blood flow, and electrocardiogram data.

    Main Results:

    • Significant tachycardia and conjunctival injection observed.
    • Blood pressure decreases when upright; no significant change or slight increase when supine.

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  • Increased limb blood flow; no significant electrocardiogram changes in normal subjects.
  • Interference with peripheral vascular reflex responses noted.

    • Conclusions:

    • Marihuana stimulates the sympathetic nervous system and blocks the parasympathetic nervous system.
    • Acute marihuana administration does not appear to present a significant cardiovascular hazard to healthy individuals.