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Hypertension.

Edward D. Frohlich1

  • 1Department of Hypertension, Alton Ochsner Medical Foundation, 1516 Jefferson Highway, New Orleans, LA 70121, USA.

Current Treatment Options in Cardiovascular Medicine
|July 11, 2001
PubMed
Summary
This summary is machine-generated.

Antihypertensive pharmacotherapy is effective and safe for managing high blood pressure and preventing cardiovascular disease complications. Treatment is recommended for elevated systolic or diastolic pressures, with specific agent selection guidance provided.

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Area of Science:

  • Cardiology
  • Pharmacology
  • Nephrology

Background:

  • Antihypertensive pharmacotherapy has a robust clinical record spanning nearly 50 years.
  • Extensive trials confirm the efficacy, safety, and feasibility of blood pressure-lowering medications.
  • Clinical experience demonstrates the ability of antihypertensive therapy to prevent and reverse cardiovascular disease complications affecting major organs.

Purpose of the Study:

  • To review available treatment options for hypertension.
  • To provide guidelines for selecting appropriate antihypertensive agents based on patient profiles.
  • To clarify indications for treating elevated blood pressure.

Main Methods:

  • Review of controlled multicenter clinical trials.
  • Analysis of extensive clinical experience with antihypertensive pharmacotherapy.

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  • Discussion of current treatment guidelines and agent selection.

    • Main Results:

    • Antihypertensive therapy is unequivocally effective and safe for controlling arterial pressure.
    • Treatment is indicated for elevated systolic (≥140 mm Hg) or diastolic (≥90 mm Hg) pressures.
    • Potential exceptions, such as borderline isolated systolic hypertension, are noted.

    Conclusions:

    • Control of elevated blood pressure is crucial for preventing and managing hypertensive cardiovascular disease.
    • Guidelines are essential for optimizing antihypertensive agent selection.
    • Further research may refine treatment strategies for specific hypertensive populations.