Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Swine platelet antigens: section report.

D Llanes1, C Arce, J P de la Lastra

  • 1Unidad Mixta Marcadores Genéticos Moleculares, Departamento de Genética, Facultad de Veterinaria, Cordoba 14005, Spain.

Veterinary Immunology and Immunopathology
|July 11, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Selection of housekeeping genes for normalization by real-time RT-PCR: analysis of Or-MYB1 gene expression in Orobanche ramosa development.

Analytical biochemistry·2008
Same author

Analysis of swine beta1 integrin (CD29) epitopes through monoclonal antibodies developed using two immunization strategies.

Hybridoma and hybridomics·2005
Same author

Molecular cloning, expression pattern and chromosomal mapping of pig CD9 antigen.

Cytogenetic and genome research·2003
Same author

A polymorphic microsatellite located on pig chromosome band 12p11-2/3p13, within the 3'-UTR of the ITGB3 gene.

Animal genetics·2002
Same author

Alternative 1-(13)C glucose infusion protocols for clinical (13)C MRS examinations of the brain.

Magnetic resonance in medicine·2001
Same author

Pulmonary infiltrates in HIV-infected patients in the highly active antiretroviral therapy era in Spain.

Journal of acquired immune deficiency syndromes (1999)·2001
Same journal

Early in vitro response to Toxoplasma gondii infection in macrophages and neutrophils from sheep immunized with a commercial vaccine.

Veterinary immunology and immunopathology·2026
Same journal

Host immune response to lumpy skin disease virus.

Veterinary immunology and immunopathology·2026
Same journal

A randomized field trial of live epizootic bovine abortion agent (EBAA) vaccine demonstrates safety and efficacy.

Veterinary immunology and immunopathology·2026
Same journal

Comparative evaluation of lateral flow immunoassay and real time PCR for detection of canine morbillivirus antigen in live attenuated vaccines.

Veterinary immunology and immunopathology·2026
Same journal

Establishment of a disease model for Mycoplasma Ovipneumoniae infectioninfection in Hu sheep and its lung transcriptomic analysis.

Veterinary immunology and immunopathology·2026
Same journal

Macrophage-mediated inflammatory responses impair mucosal barrier components and promote goblet cell loss during Eimeria tenella infection in chickens.

Veterinary immunology and immunopathology·2026
See all related articles

Researchers identified 14 antibodies that bind to swine platelets. Six antibodies recognized known swine CD markers, while one identified a human CD47 marker, aiding platelet research.

Area of Science:

  • Immunology
  • Hematology
  • Veterinary Science

Background:

  • Platelets play crucial roles in hemostasis and immune responses.
  • Characterizing platelet surface markers is essential for understanding swine hematology and immunology.
  • Limited information exists on swine platelet-specific antigens.

Purpose of the Study:

  • To identify and characterize novel antibodies that bind to swine platelets.
  • To expand the repertoire of known swine platelet surface markers.
  • To facilitate further research into swine platelet function and immunology.

Main Methods:

  • Screening of 14 antibodies against resting and activated swine platelets.
  • Utilizing known swine and human CD markers for antibody characterization.

Related Experiment Videos

  • Employing flow cytometry and immunological assays.

    • Main Results:

    • 14 antibodies demonstrated labeling of swine platelets.
    • Six antibodies recognized previously characterized swine CD markers (CD29, CD41/61, CD46).
    • One antibody recognized human CD47, with another potentially recognizing its swine homologue; five antibodies remained unclustered.

    Conclusions:

    • The study successfully identified multiple antibodies targeting swine platelets.
    • This expands the available tools for swine platelet research.
    • The findings contribute to a better understanding of swine platelet surface markers and their potential roles.