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Related Experiment Video

Updated: Jul 8, 2026

A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry

A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry

Published on: June 5, 2019

Swine platelet antigens: section report.

D Llanes¹, C Arce, J P de la Lastra

¹Unidad Mixta Marcadores Genéticos Moleculares, Departamento de Genética, Facultad de Veterinaria, Cordoba 14005, Spain.

Veterinary Immunology and Immunopathology

|July 11, 2001

Summary

This summary is machine-generated.

Researchers identified 14 antibodies that bind to swine platelets. Six antibodies recognized known swine CD markers, while one identified a human CD47 marker, aiding platelet research.

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Area of Science:

Immunology
Hematology
Veterinary Science

Background:

Platelets play crucial roles in hemostasis and immune responses.
Characterizing platelet surface markers is essential for understanding swine hematology and immunology.
Limited information exists on swine platelet-specific antigens.

Purpose of the Study:

To identify and characterize novel antibodies that bind to swine platelets.
To expand the repertoire of known swine platelet surface markers.
To facilitate further research into swine platelet function and immunology.

Main Methods:

Screening of 14 antibodies against resting and activated swine platelets.
Utilizing known swine and human CD markers for antibody characterization.
Employing flow cytometry and immunological assays.

Main Results:

14 antibodies demonstrated labeling of swine platelets.
Six antibodies recognized previously characterized swine CD markers (CD29, CD41/61, CD46).
One antibody recognized human CD47, with another potentially recognizing its swine homologue; five antibodies remained unclustered.

Conclusions:

The study successfully identified multiple antibodies targeting swine platelets.
This expands the available tools for swine platelet research.
The findings contribute to a better understanding of swine platelet surface markers and their potential roles.