Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sequence-sensitive subcomponents of P300: topographical analyses and dipole source localization.

I Jentzsch1, W Sommer

  • 1Department of Psychology, Humboldt-University Berlin, Germany. ines@psy.gla.ac.uk

Psychophysiology
|July 12, 2001
PubMed
Summary

Sequential effects impact P300 amplitude and reaction time. This study confirms dissociable P300 subcomponents, with a sequence-sensitive one originating from a deep mesial source.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Eye contact in active and passive viewing: Event-related brain potential evidence from a combined eye tracking and EEG study.

Neuropsychologia·2020
Same author

Large lateralized EDAN-like brain potentials in a gaze-shift detection task.

Psychophysiology·2019
Same author

Role for primary immunosuppression with everolimus after pulmonary transplantation.

Transplant immunology·2018
Same author

Single lung transplantation from a donor 8 months after double lung transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2018
Same author

Association of Higher CD4<sup>+</sup> CD25<sup>high</sup> CD127<sup>low</sup> , FoxP3<sup>+</sup> , and IL-2<sup>+</sup> T Cell Frequencies Early After Lung Transplantation With Less Chronic Lung Allograft Dysfunction at Two Years.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2016
Same author

Dual energy CT allows for improved characterization of response to antiangiogenic treatment in patients with metastatic renal cell cancer.

European radiology·2016

Area of Science:

  • Cognitive Neuroscience
  • Electrophysiology

Background:

  • P300 amplitude and reaction time (RT) are influenced by preceding event sequences.
  • Previous research suggested sequential effects might involve distinct P300 subcomponents.
  • Global P300 changes hinted at a sequence-specific subcomponent separate from the classical parietal P300.

Purpose of the Study:

  • To provide confirming evidence for dissociable subcomponents of the P300.
  • To investigate the source and distribution of sequence-sensitive P300 subcomponents.

Main Methods:

  • Utilized independent component analysis (ICA) to separate P300 subcomponents.
  • Applied dipole source analysis to identify the origin of identified subcomponents.
  • Conducted two experiments to examine sequential effects on P300.

Related Experiment Videos

Main Results:

  • Independent component analysis successfully separated a centrally distributed sequence-sensitive subcomponent from a parietal subcomponent.
  • Dipole source analysis localized the sequence-sensitive subcomponent to a deep mesial brain region.
  • Observed apparent lateralization of the sequence-sensitive component due to overlap with somatosensory activity.

Conclusions:

  • The P300 comprises dissociable subcomponents sensitive to event sequences.
  • A distinct, sequence-sensitive P300 subcomponent originates from a deep mesial source.
  • Somatosensory reafference may influence the observed topography of this subcomponent.