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Chasing hyponatraemia: unusual presentation.

M Tripathi1, C C Sanjeev, A K Roy

  • 1Department of Neurology, St. John's Medical College Hospital, Bangalore, India.

Neurology India
|July 12, 2001
PubMed
Summary
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Persistent hyponatraemia in two women led to the discovery of pituitary disorders. Investigations revealed a pituitary microadenoma in one and empty sella syndrome in the other, highlighting these conditions as potential causes.

Area of Science:

  • Neurology
  • Endocrinology

Background:

  • Recurrent neurological symptoms like headache, vertigo, vomiting, and altered sensorium can be challenging to diagnose.
  • Persistent hyponatraemia is an electrolyte imbalance that can present with non-specific neurological signs.

Observation:

  • Two female patients in their sixth decade presented with recurrent episodes of headache, vertigo, vomiting, and altered sensorium.
  • Both patients exhibited persistent hyponatraemia as the sole initial laboratory abnormality.

Findings:

  • Detailed investigations identified a pituitary aetiology in both cases.
  • One patient was diagnosed with a pituitary microadenoma, while the other had empty sella syndrome.

Implications:

  • This case series underscores the importance of considering pituitary disorders in patients with unexplained neurological symptoms and persistent hyponatraemia.

Related Experiment Videos

  • Early diagnosis and appropriate management of pituitary microadenoma and empty sella syndrome are crucial for improving patient outcomes.