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Related Experiment Videos

Vertebrate gastrulation: calcium waves orchestrate cell movements.

M Tada1, M L Concha

  • 1Department of Anatomy and Developmental Biology, University College London, Gower Street, WC1E 6BT, London, UK. mtada@ucl.ac.uk

Current Biology : CB
|July 13, 2001
PubMed
Summary

Intercellular calcium signals coordinate cell movements during Xenopus gastrulation. This cell communication mechanism drives convergent extension, a key developmental process.

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Area of Science:

  • Developmental Biology
  • Cell Biology
  • Molecular Biology

Background:

  • Intercellular calcium signaling plays a crucial role in various cellular processes.
  • Gastrulation in Xenopus involves complex cell movements to establish body axes.

Purpose of the Study:

  • To investigate the association between intercellular calcium signals and convergent extension movements.
  • To elucidate the role of cell communication in Xenopus gastrulation.

Main Methods:

  • Observational studies on Xenopus embryos.
  • Analysis of calcium signal propagation.
  • Monitoring of cell movements during gastrulation.

Main Results:

  • A strong correlation was observed between intercellular calcium signal propagation and convergent extension.

Related Experiment Videos

  • Calcium signals facilitate communication among large cell populations.
  • This communication orchestrates coordinated cell movements essential for gastrulation.

    • Conclusions:

    • Intercellular calcium signals are integral to the generation of convergent extension movements.
    • Cellular communication via calcium signaling is a fundamental mechanism driving Xenopus gastrulation.