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A role for nuclear lamins in nuclear envelope assembly.

R I Lopez-Soler1, R D Moir, T P Spann

  • 1Department of Cell and Molecular Biology, Northwestern University Medical School, 303 East Chicago Avenue, Chicago, IL 60611, USA.

The Journal of Cell Biology
|July 13, 2001
PubMed
Summary

A peptide from Xenopus lamin B3 (LB3T) blocks nuclear envelope assembly by inhibiting lamin polymerization. This prevents chromatin decondensation and nuclear membrane formation, revealing key steps in nuclear envelope formation.

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