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Related Experiment Videos

Delayed facial palsy after stapedectomy.

J J Shea1, X Ge

  • 1Shea Ear Clinic, Memphis, Tennessee 38119, USA.

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [And] European Academy of Otology and Neurotology
|July 13, 2001
PubMed
Summary
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Delayed facial palsy after stapedectomy, a rare complication, may be linked to latent herpesvirus activation. Early intervention with acyclovir shows promise in preventing this condition.

Area of Science:

  • Otology and Neurotology
  • Facial Nerve Surgery
  • Viral Pathogenesis

Background:

  • Stapedectomy is a common procedure for hearing loss.
  • Delayed facial palsy (DFP) is a rare but serious complication following stapedectomy.
  • Understanding the incidence and etiology of DFP is crucial for patient safety.

Observation:

  • DFP occurred in 0.51% of 2152 stapedectomy procedures.
  • Onset of DFP ranged from 5 to 16 days post-surgery.
  • Risk factors included facial canal dehiscence, chorda tympani manipulation, Gelfoam reaction, and sinusitis.

Findings:

  • Elevated antibody titers for varicella zoster virus and herpes simplex virus were observed in patients with DFP.
  • These serologic findings suggest reactivation of latent herpesviruses.

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  • Mechanical irritation during surgery may trigger viral reactivation.

    • Implications:

    • DFP following stapedectomy warrants investigation for viral reactivation.
    • The antiviral medication acyclovir may be beneficial in preventing DFP in susceptible patients.
    • Further research into prophylactic antiviral use in high-risk cases is recommended.