[Intramedullary metastases and syringomyelic cavities]
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Minimally Invasive Cisterna Magna Injection Model for Leptomeningeal Metastasis Studies in Mice
Published on: May 23, 2025
1Service de Radiologie, Centre Hospitalier de Pau, 4 Boulevard Hauterive, BP 1156, 64046 Pau Université Cedex, France.
Abstract:
Intramedullary metastases from a non neurogenic cancer are relatively rare, representing approximately 1-2,1% of metastatic sites according to published autopsy reports. Their association with syrinx is extremely rare. Four cases have been described in the last 30 years. We report the case of a 60 year old female with past medical history of Peutz-Jeghers disease, who presented with clinical signs suggestive of medullary lesions of the cervical spine. MR imaging showed tumoral lesions at different levels associated with syrinx. Surgical biopsy confirmed the intramedullary lesions which, by pathology, were found to be of metastatic origin.
