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Limonoids and phytol derivatives from Cedrela sinensis.

X D Luo¹, S H Wu, Y B Ma

¹Laboratory of Phytochemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, P.R. China. x-dluo@hotmail.com

|July 14, 2001

Summary

Researchers identified two novel compounds, cedrellin and 2,6,10,15-phytatetraene-14-ol, from Cedrela sinensis leaves. These, along with five known compounds, were structurally characterized using advanced spectral methods.

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Area of Science:

Natural Product Chemistry
Phytochemistry
Organic Chemistry

Background:

Cedrela sinensis is a plant species known for its potential bioactive compounds.
Phytochemical investigations are crucial for discovering novel natural products with therapeutic potential.

Purpose of the Study:

To isolate and characterize new and known chemical constituents from the leaves of Cedrela sinensis.
To elucidate the structures of isolated compounds using comprehensive spectroscopic analyses.

Main Methods:

Extraction of compounds from Cedrela sinensis leaves.
Isolation of compounds using chromatographic techniques.
Structure elucidation employing one-dimensional (1D) and two-dimensional (2D) nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry.

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Main Results:

Two new compounds, cedrellin (1) and 2,6,10,15-phytatetraene-14-ol (2), were successfully isolated.
Five known compounds, including phytol derivatives and acetates, were also identified.
The structures of all isolated compounds were confirmed through detailed spectral data analysis.

Conclusions:

The phytochemical investigation of Cedrela sinensis leaves yielded two new compounds and five known ones.
The structural elucidation confirmed the presence of unique chemical entities within this plant species.
This study contributes to the understanding of the chemical diversity of Cedrela sinensis.