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Related Experiment Videos

[Preparation and application of polylactide].

J Liu1, Y Liu

  • 1No. 9 People's Hospital, Shanghai Second Medical University, Shanghai Biomaterials Research and Test Center, Shanghai 200023.

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi
|July 14, 2001
PubMed
Summary

Polylactide (PLA) and its copolymers are biocompatible, biodegradable polymers with no toxicity. Further research is needed to improve their properties for wider applications in medicine and degradable plastics.

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Area of Science:

  • Polymer Science
  • Biomaterials Engineering
  • Materials Science

Background:

  • Polylactide (PLA) and its copolymers are biodegradable and biocompatible polymers.
  • These materials exhibit no toxicity and are absorbable, leading to increased research and development.
  • Applications are expanding, particularly in medicine and pharmacy.

Purpose of the Study:

  • To review the preparation methods for polylactide and its copolymers.
  • To evaluate existing tests for assessing the degradation properties of these polymers.
  • To identify areas for improvement in the properties and technological level of polylactide and its copolymers.

Main Methods:

  • Review of existing literature on polylactide and copolymer preparation.
  • Analysis of established degradation testing methods for polylactide and copolymers.

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  • Identification of current limitations and future research directions.

    • Main Results:

    • Three primary methods exist for preparing polylactide and its copolymers.
    • Current degradation tests, despite over thirty years of use, have inherent defects.
    • The properties and technological advancements of these polymers require further enhancement for specific applications.

    Conclusions:

    • Polylactide and its copolymers hold significant potential for medical and degradable plastic applications.
    • Industrialization of polylactide manufacturing could lead to widespread use.
    • Continued research is essential to overcome existing limitations and optimize material performance.