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Published on: March 14, 2018
The Modified Checklist for Autism in Toddlers: an initial study investigating the early detection of autism and
D L Robins1, D Fein, M L Barton
1Department of Psychology, University of Connecticut, Storrs 06269-1020, USA.
Insights
Early detection of autism in toddlers is crucial for better outcomes. The Modified Checklist for Autism in Toddlers (M-CHAT) shows promise for identifying children with autism spectrum disorder.
Area of Science:
- Child Development
- Developmental Pediatrics
- Autism Spectrum Disorder Research
Background:
- Autism spectrum disorder (ASD) is a severe developmental disorder that is challenging to diagnose in early childhood.
- Early intervention for children with ASD significantly improves long-term prognoses and developmental trajectories.
Purpose of the Study:
- To evaluate the effectiveness of the Modified Checklist for Autism in Toddlers (M-CHAT) as a screening tool for early autism detection.
- To identify specific M-CHAT items most effective in discriminating between toddlers with and without ASD.
Main Methods:
- The M-CHAT, a 23-item yes/no questionnaire, was administered to screen 1,293 toddlers.
- Children who underwent diagnostic/developmental evaluations (n=58) were analyzed, with 39 diagnosed with ASD.
- Statistical analysis was performed to determine the discriminative power of individual items and the total checklist score.
Main Results:
- The M-CHAT screening identified toddlers at risk for autism spectrum disorder.
- Six specific items related to social relatedness and communication demonstrated the highest discriminability between children with and without ASD.
- Optimized cutoff scores were established for both the key items and the overall M-CHAT checklist.
Conclusions:
- The Modified Checklist for Autism in Toddlers (M-CHAT) is a valuable and promising instrument for the early detection of autism spectrum disorder in toddlers.
- Targeted screening using specific M-CHAT items can enhance diagnostic accuracy for early identification of ASD.
Abstract:
Autism, a severe disorder of development, is difficult to detect in very young children. However, children who receive early intervention have improved long-term prognoses. The Modified Checklist for Autism in Toddlers (M-CHAT), consisting of 23 yes/no items, was used to screen 1,293 children. Of the 58 children given a diagnostic/developmental evaluation, 39 were diagnosed with a disorder on the autism spectrum. Six items pertaining to social relatedness and communication were found to have the best discriminability between children diagnosed with and without autism/PDD. Cutoff scores were created for the best items and the total checklist. Results indicate that the M-CHAT is a promising instrument for the early detection of autism.
Related Concept Videos
Autism Spectrum Disorder
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
