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Increased detection of herpesvirus DNA in idiopathic pulmonary fibrosis

Y W Tang1, J Johnson, R Cruz-Gervis

  • 1Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2605, USA. yiwei.tang@vanderbilt.edu

Chest
|July 14, 2001
PubMed
Abstract

No abstract available in PubMed .

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Herpes

Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...