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[Fat distribution and metabolism].

J P Després1, I Lemieux, A Tchernof

  • 1L'Institut de cardiologie de Québec, Centre de recherche de l'Hôpital Laval, Sainte-Foy (Québec), Canada. jean-pierre.despres@crchul.ulaval.ca

Diabetes & Metabolism
|July 14, 2001
PubMed
Summary
This summary is machine-generated.

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Adipose tissue distribution, particularly visceral fat, impacts type 2 diabetes and cardiovascular disease risk. Targeted reduction of abdominal fat through weight loss can improve metabolic health and insulin sensitivity.

Area of Science:

  • Endocrinology and Metabolism
  • Cardiovascular Science
  • Human Physiology

Context:

  • Adipose tissue distribution differs between sexes, with men accumulating visceral fat and women gluteo-femoral fat.
  • Aging and menopause are associated with increased visceral adipose tissue accumulation.
  • Visceral adipose tissue is linked to metabolic complications, increasing risks for type 2 diabetes and cardiovascular diseases.

Purpose:

  • To highlight the significance of adipose tissue distribution in metabolic and cardiovascular health.
  • To underscore the role of visceral adipose tissue in disease etiology.
  • To emphasize the therapeutic potential of targeting abdominal fat reduction.

Summary:

  • Men accumulate visceral adipose tissue more than women, a pattern that shifts with age and menopause.

Related Experiment Videos

  • Increased visceral fat contributes to metabolic syndrome, type 2 diabetes, and cardiovascular disease.
  • Weight loss programs can selectively reduce visceral fat, improving lipid profiles and insulin sensitivity.

    • Impact:

    • Adipose tissue distribution is a crucial factor in patient evaluation for metabolic and cardiovascular risk.
    • Abdominal adipose tissue quantity serves as a key therapeutic target for managing cardiovascular disease risk.
    • Understanding fat distribution aids in personalized risk assessment and treatment strategies.