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[Gregg phenomenon and garden hose effect].

J D Schipke1, D Frehen

  • 1Zentrum für Operative Medizin I Forschungsgruppe Experimentelle Chirurgie Universität Düsseldorf 40225 Düsseldorf, Germany. schipkej@uni-duesseldorf.de

Zeitschrift Fur Kardiologie
|July 17, 2001
PubMed
Summary

Improved coronary perfusion enhances heart muscle oxygen use and function, a concept known as the Gregg phenomenon. This study differentiates it from the hydraulic

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Area of Science:

  • Cardiovascular Physiology
  • Cardiac Mechanics
  • Coronary Circulation

Context:

  • Cardiac function influences myocardial oxygen consumption and coronary perfusion.
  • The Gregg phenomenon describes how improved coronary perfusion increases myocardial oxygen consumption and contractile function.
  • The 'gardenhose effect' offers a hydraulic explanation for the Gregg phenomenon.

Purpose:

  • To differentiate the Gregg phenomenon from the 'gardenhose effect'.
  • To critically evaluate both the Gregg phenomenon and the 'gardenhose effect' in cardiovascular physiology.

Summary:

  • The Gregg phenomenon, observed 40 years ago, shows improved coronary perfusion enhances myocardial oxygen consumption and contractile function.
  • Later experiments by Arnold et al. demonstrated improved ventricular function with increased perfusion pressure, termed the 'gardenhose effect'.
  • This work aims to distinguish these related but distinct concepts in cardiac physiology.

Impact:

  • Clarifies the mechanisms underlying the relationship between coronary perfusion and cardiac function.
  • Provides a critical evaluation of established physiological phenomena.
  • Enhances understanding of cardiac energetics and mechanics.

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