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[Pathogenesis of mural thrombi in idiopathic cardiomyopathy]
Insights
Idiopathic cardiomyopathy can lead to mural thrombi. Severe cardiac dilatation and abnormal blood flow in the heart are key factors in developing these blood clots.
Area of Science:
- Cardiovascular Pathology
- Morphological Studies
Abstract:
Thirty-two hearts from patients with idiopathic cardiomyopathy were examined postmortem. A comparative morphological study of the human hearts and of hearts from cardiomyopathic hamsters, rabbits and baboons indicates that severe cardiac dilatation with intracavitary stasis and abnormal turbulent blood flow are the most important factors in the pathogenesis of mural thrombi in idiopathic cardiomyopathy.