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Related Experiment Videos

Presumed sertraline maculopathy.

E C Sener1, H Kiratli

  • 1Department of Ophthalmology, Hacettepe University School of Medicine, Ankara, Turkey.

Acta Ophthalmologica Scandinavica
|July 17, 2001
PubMed
Summary
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A woman developed bilateral maculopathy after taking sertraline hydrochloride (a serotonin reuptake inhibitor). Macular lesions resolved after stopping the drug, but vision did not fully recover.

Area of Science:

  • Ophthalmology
  • Neuroscience

Background:

  • Selective serotonin reuptake inhibitors (SSRIs) like sertraline are widely prescribed.
  • Ocular side effects of SSRIs are uncommon but can be serious.

Observation:

  • A case report details a woman experiencing simultaneous bilateral maculopathy.
  • The condition was presumed to be linked to sertraline hydrochloride intake.

Findings:

  • Ocular examinations revealed generalized sensitivity reduction and central scotomas on automated static perimetry.
  • Macular lesions resolved within six months of sertraline discontinuation.
  • Despite resolution of lesions, visual acuity and psychophysical test abnormalities persisted over twenty months.

Implications:

Related Experiment Videos

  • Patients on sertraline should be aware of the potential risk of maculopathy.
  • Regular ophthalmic examinations are recommended for early detection of visual alterations in patients taking sertraline.