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Reversing insect adaptation to transgenic insecticidal plants
1Department of Entomology, The University of Arizona, 410 Forbes Building, Tucson, AZ 85721, USA. ycarrier@ag.arizona.edu
Proceedings. Biological Sciences
|July 17, 2001
Summary
The refuge-high-dose strategy can delay insect resistance to transgenic crops. Reversing resistance requires non-recessive costs, low initial resistance frequency, large refuges, and incomplete resistance.
Area of Science:
- Agricultural Entomology
- Genetics
- Pest Management
Background:
- Transgenic plants utilize the refuge-high-dose strategy to delay insect adaptation.
- This strategy relies on non-transgenic plants for susceptible insect survival.
- Previous models identified key requirements for the strategy's success.
Purpose of the Study:
- To explore conditions that prevent or reverse insect resistance evolution.
- To understand observed decreases in resistance frequency.
- To improve management strategies for insect resistance.
Main Methods:
- Analytical and simulation models were employed.
- Investigated conditions for resistance evolution and reversal.
- Assumed random mating and recessive or nearly recessive inheritance.
Main Results:
- Non-recessive costs of resistance favor reversal.
- Low initial resistance allele frequency is crucial for reversal.
- Large refuges, incomplete resistance, and density-independent growth in refuges also favor reversal.
Conclusions:
- The refuge-high-dose strategy's success depends on specific genetic and ecological factors.
- Reversing established resistance is possible under certain conditions.
- Management strategies can be refined by considering these factors to sustain transgenic trait efficacy.