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The essence of excitation
R J Reimer1, R T Fremeau, E E Bellocchio
1Departments of Neurology and Physiology, Graduate Programs in Neuroscience, Cell Biology and Biomedical Sciences, University of California, San Francisco, School of Medicine, 513 Parnassus Avenue, 94143-0435, USA.
Current Opinion in Cell Biology
|July 17, 2001
Abstract:
The amino acid glutamate is the major excitatory neurotransmitter in a range of organisms from Caenorhabditis elegans to mammals, and it mediates the information processing that underlies essentially all behavior. Recent advances in our understanding of glutamate storage and release now illuminate how this ubiquitous amino acid can function as a signalling molecule.