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Oligodendroglial ganglioglioma with anaplastic features arising from the thalamus
M D Johnson1, M T Jennings, S T Toms
1Department of Pathology, Vanderbilt Medical School and Nashville Veteran's Administration Medical Center, Nashville, TN 37212, USA. Mahlon.Johnson@mcmail.vanderbilt.edu
Abstract:
Anaplastic gangliogliomas with an oligodendroglial component are exceedingly rare tumors of uncertain growth potential. We report a 17-year-old female with a massive ganglioglioma containing anaplastic oligodendroglioma apparently arising from the thalamus. Two weeks after partial resection, she was started on a regimen including escalated doses of topotecan in combination with a fixed-dosage intensification regimen of cisplatin, cyclophosphamide and vincristine with subsequent hyperfractionated external beam radiotherapy. She currently has stable disease.