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[Nephrogenic adenoma of the bladder: metaplasia or embryologic alteration?]
M A Sousa Escandón1, J Pérez Valcárcel, M González Fernández
1Servicio de Urología, Hospital Comarcal de Monforte, Lugo.
Objectives:
To present a new case of nephrogenic adenoma of the bladder and to review the current concepts on the etiopathogenesis of this lesion.
Clinical Case:
Seventy years old female with repetitive haematuria who was diagnosed as having a nephrogenic adenoma of the bladder which was extirpated by cold biopsy forceps. No tumoral relapse was detected after 16 months of follow up.
Discussion:
In the light of the present knowledges, the origin of nephrogenic adenoma is a phenomenon of urothelial metaplasia due to a chronic irritative stimulus wich would lead a cellular proliferation with potentialities to originate mesonephric tissues and which starting point could be on not completely involutioned mesonephric cellular rests and/or on de-differentiated mature urothelial cells.