Related Experiment Videos
Susac syndrome: a vasospastic disorder?
J Flammer1, H Kaiser, T Haufschild
1University Eye Clinic, Department of Ophthalmology, Basel, Switzerland. Josef.Flammer@unibas.ch
Purpose:
The Susac syndrome is a microangiopathy that leads to visual symptoms, hearing loss and neurological symptoms.
Case Report:
We report on a young woman suffering from this syndrome who also presented the following signs and symptoms typical of a vasospastic syndrome; 1) a history of cold hands, low blood pressure and migraine; 2) a typical alteration of conjunctival vessels; 3) prolonged flow arrest time after cooling in nailfold capillaromicroscopy; 4) increased resistivity in the orbital vessels measured by color Doppler imaging; and 5) an increased plasma level of endothelin-1.
Conclusions:
We postulate that the Susac syndrome is a manifestation of the vasospastic syndrome.