Related Experiment Videos
Diastereomeric diterpenes from Coleus blumei
C Y Ragas1, V F Templora, J A Rideout
1Chemistry Department, De La Salle University, Manila, Philippines. coscyr@mail.dlsu.edu.ph
Chemical & Pharmaceutical Bulletin
|July 18, 2001
Abstract:
The chloroform extract of the air-dried leaves of Coleus blumei afforded a mixture of diastereomers of a new abietane type diterpene whose structures were elucidated by extensive one and two dimensional (ID, 2D) NMR and mass spectrometry. Acetylation of the mixture afforded a single compound. Antimicrobial tests on the diterpene indicate that it is active against Bacillus subtilis, Pseudomonas aeruginosa and Candida albicans.