Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Exocrine pancreatic function after upper abdominal surgery.

Y Suda, M Shiraso, T Sato

The Tohoku Journal of Experimental Medicine

|April 1, 1975

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Relationship between inhibitor of extrathyroidal 5'-deiodinase activity and serum free fatty acid in children with nonthyroidal illness and acute ketosis.

Endocrinologia japonica·1992

Same author

Preferential activation of phospholipase A2 by low concentrations of phosphatidic acid with long-chain fatty acids in rabbit platelets.

Journal of biochemistry·1992

Same author

Innervation of an aberrant digastric muscle in the posterior thigh: stratified relationships between branches of the inferior gluteal nerve.

Journal of anatomy·1992

Same author

A simple stimulator for periodontal mechanoreceptors in human subjects.

Journal de biologie buccale·1992

Same author

Blockade of 2,4-dinitrophenol induced ATP sensitive potassium current in guinea pig ventricular myocytes by class I antiarrhythmic drugs.

Cardiovascular research·1992

Same author

Mechanisms of desensitization in delayed cutaneous hypersensitivity--modulation of T-cell response by haptenized amino acid.

The Journal of dermatology·1992

Same journal

Demographic and Geographical Distribution of Dentists in Japan: Analysis of National Data in 1996, 2006, and 2016.

The Tohoku journal of experimental medicine·2026

Same journal

Association of Myeloid Derived Suppressor Cells and Immunosuppressive Elements with Disease and Prognosis in Pancreatic Adenocarcinoma.

The Tohoku journal of experimental medicine·2026

Same journal

Reduced EphB2 Expression Due to Hypermethylation in DLBCL-NOS Is Associated with Prognosis.

The Tohoku journal of experimental medicine·2026

Same journal

Dynamic Expression of Podoplanin Correlates with Synovitis Severity in a Lipopolysaccharide-Induced Rabbit Arthritis Model.

The Tohoku journal of experimental medicine·2026

Same journal

Fifteen Years On: A Retrospective Institutional Case Study of Soma General Hospital Following the 2011 Fukushima Daiichi Nuclear Accident.

The Tohoku journal of experimental medicine·2026

Same journal

Optimizing Outcomes in ICU Pulmonary Infections: The Role of Comprehensive Nursing Intervention.

The Tohoku journal of experimental medicine·2026

See all related articles

Postoperative upper abdominal surgery impacts exocrine pancreatic function. Pancreatic fibrosis and surgical type, like Billroth II gastrectomy, significantly reduce pancreatic secretion, affecting bicarbonate and amylase output.

Area of Science:

Gastroenterology
Surgical Oncology
Digestive Physiology

Background:

Upper abdominal surgery can alter pancreatic function.
Exocrine pancreatic secretion is regulated by hormones and neural pathways.
Pancreatic fibrosis is a known factor affecting pancreatic health.

Purpose of the Study:

To quantify the impact of upper abdominal surgery on exocrine pancreatic secretion.
To correlate pancreatic fibrosis with exocrine function post-surgery.
To compare the effects of different surgical procedures on pancreatic secretion.

Main Methods:

Observation of daily pancreatic flow, bicarbonate, and amylase output in 15 postoperative patients.
Histometrical assessment of pancreatic fibrosis.

Related Experiment Videos

Correlation analysis between pancreatic fibrosis and exocrine secretion.

Comparison of secretion levels across different surgical types (Billroth I, Billroth II, distal pancreatectomy, pancreatoduodenectomy).

Main Results:

Exocrine pancreatic secretion correlated with pancreatic fibrosis.
Billroth II gastrectomy reduced secretion to 60-70% of Billroth I.
Distal pancreatectomy's secretion reduction matched resected volume.
Pancreatoduodenectomy caused greater-than-expected secretion depression due to hormonal and neural disruption.

Conclusions:

Upper abdominal surgery significantly impairs exocrine pancreatic secretion.
Pancreatic fibrosis is a key determinant of secretory capacity post-surgery.
Surgical technique, particularly Billroth II gastrectomy and pancreatoduodenectomy, profoundly affects pancreatic function, with the latter involving hormonal and neural mechanisms.