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Updated: Jun 23, 2026

A Protein Suspension-Trapping Sample Preparation for Tear Proteomics by Liquid Chromatography-Tandem Mass Spectrometry
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SEA-TROSY (solvent exposed amides with TROSY): a method to resolve the problem of spectral overlap in very large

M Pellecchia1, D Meininger, A L Shen

  • 1Triad Therapeutics Inc., 5820 Nancy Ridge Dr., San Diego, California 92121, USA. mpellecchia@triadt.com

Journal of the American Chemical Society
|July 18, 2001
PubMed
Abstract

No abstract available in PubMed .

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Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...

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