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Updated: Oct 5, 2026

A Whole Mount In Situ Hybridization Method for the Gastropod Mollusc Lymnaea stagnalis
Published on: March 15, 2016
Mollusk-derived growth factor: cloning and developmental expression in the central nervous system and reproductive
1Marine Biomedical Institute and Department of Anatomy and Neurosciences, University of Texas Medical Branch, Medical Research Building, Galveston, TX 77555-1043, USA. dakalal@utmb.edu
Abstract:
We have isolated and characterized an atrial gland cDNA that corrects the previously reported sequence for Aplysia atrial gland granule-specific antigen (AGSA), a glycoprotein of unknown function. We designated the protein mollusk-derived growth factor (MDGF) to distinguish the revised sequence from AGSA and to emphasize its similarity to an insect-derived growth factor (IDGF). We describe MDGF mRNA expression that suggests a possible role during embryonic development and CNS injury repair.

