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Nicotine inhibits estrogen response element binding in the rat brain
A S Shingo1, M Yonezawa, K Sakurai
1Research Institute, Hyogo University, Japan. sheala@mcn.ne.jp
Journal of Neural Transmission (Vienna, Austria : 1996)
|July 19, 2001
Abstract:
General injection of nicotine induced an immediate and marked inhibition of estrogen response element (ERE) binding in the rat brain. Either mecamylamine or nifedipine fully antagonized the ERE binding-inhibiting effect of nicotine.