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Updated: Oct 5, 2026

Tissue Engineering by Intrinsic Vascularization in an In Vivo Tissue Engineering Chamber
Published on: May 30, 2016
[The intraosseal route. When the veins have disappeared]
P E Orgiler Uranga1, J M Navarro Arnedo, S De Haro Marín
1Diplomados en Enfermería Unidad de Cuidados Intensivos Pediátricos, Spain.
Insights
The intraosseous route offers rapid, safe, and effective emergency vascular access, particularly for children when other methods fail. This method is crucial for timely fluid and drug delivery in critical pediatric situations.
Area of Science:
- Emergency Medicine
- Pediatric Critical Care
- Vascular Access Techniques
Context:
- Difficult or impossible vascular access is a critical challenge in pediatric emergencies.
- Peripheral or central venous cannulation can be time-consuming and may fail in critically ill children.
- Rapid administration of fluids, electrolytes, and medications is vital for life-saving interventions.
Purpose:
- To evaluate the utility and efficacy of the intraosseous (IO) route for emergency vascular access in pediatric patients.
- To highlight the IO route as a viable alternative when traditional venous access is not feasible.
- To review the indications, optimal insertion sites, administration protocols, and potential complications of IO access.
Summary:
- The intraosseous route provides rapid, easy, and effective vascular access, especially in children under six years old.
- It is indicated in emergencies when peripheral or central cannulation is too slow and the child's life is at risk.
- The proximal or distal tibia and distal femur are preferred insertion sites, with administration similar to the venous route.
Impact:
- The intraosseous route serves as a critical alternative for emergency vascular access, improving patient outcomes in pediatric emergencies.
- It facilitates timely delivery of essential fluids, medications, and electrolytes, as well as specimen collection for laboratory analysis.
- Complications are rare, with compartmental syndrome being the most serious, underscoring the safety and broad applicability of this technique.
Abstract:
The aim of this study was to demonstrate the usefulness of the intraosseal route in providing emergency vascular access, especially in children, when vascular access through peripheral or central routes is difficult or impossible. A literature review revealed that the intraosseal route provides rapid, easy and effective access to the vascular system, especially in children under the age of 6 years. This route is indicated when, in emergencies, peripheral or central cannulation is too slow and the child's life is at risk. The most appropriate sites of insertion are the proximal or distal segments of the tibia and the distal segment of the femur. The administration of fluids, electrolytes and drugs through the intraosseal route is similar to that through the venous route. Complications are rare, the most serious being compartmental syndrome. In addition to providing an alternative route for the infusion of drugs and other substances into the bloodstream, the intraosseal route also provides access to the vascular system when samples for laboratory investigations are required. In conclusion, the intraosseal route provides rapid, safe and easy access to the vascular system. Complications are infrequent and there are few contraindications.
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