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Islet transplantation: present clinical situation and future aspects
R G Bretzel1, M Brendel, M Eckhard
1Third Medical Department and Policlinic, Justus-Liebig-University, Giessen, Germany. reinhard.bretzel@innere.med.uni-giessen.de
Abstract:
Beta-cell replacement either by pancreatic organ or islet cell transplantation is the only treatment to achieve an insulin-independent, normoglycemic state and to avoid hypoglycemic episodes in patients with type 1 diabetes mellitus. This article will review the state-of-the-art in clinical islet cell transplantation at the dawn of the new millennium and will provide an outlook on the basis of extended personal experience.