Related Experiment Video
Updated: Aug 18, 2026

In Situ Characterization of Hydrated Proteins in Water by SALVI and ToF-SIMS
Published on: February 15, 2016
Glass transition in protein hydration water
1Laboratoire de Physique, Ecole Normale Supérieure de Lyon, 46 allée d'Italie, 69364 Lyon Cedex 07, France.
Abstract:
A model of two-dimensional water is studied in order to analyze recent dielectric measurements on protein hydration water. The frustration introduced by the coupling of the water molecules to the protein surface prevents a true crystallization and induces a smooth transition to a glassy state that is detected by its structure factor and the stretched exponential behavior of the cage correlation function that measures the rate of change of the hydrogen bond network around each molecule. The spectrum of the fluctuations in the vicinity of the glass transition exhibits 1/f(alpha) noise in agreement with the dielectric measurements. The results suggest that two-dimensional water, which can be probed by dielectric measurements, could be an interesting system to study the glassy behavior of water.
More Related Videos
Related Concept Videos
Protein Folding
Membrane Fluidity
Noncovalent Attractions in Biomolecules
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
Hydrogen bonding results from the electrostatic attraction of a hydrogen atom covalently bonded to a strong-electronegative atom like oxygen,...
Membrane Fluidity
Mosaic nature of the membrane
The mosaic characteristic of the membrane helps the plasma membrane remain fluid. The integral proteins and lipids exist as separate but loosely-attached molecules in the membrane. The membrane is a relatively...
Aquaporins
Protein Folding
Protein Structure Is Critical to Its Biological Function
Proteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...

